SCHEMBL8359349

SCHEMBL8359349

CCCCC1=Cc2ccccc2C1[Hf](Cl)(Cl)(C1C(CCCC)=Cc2ccccc21)[SiH](C)C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8355992 0.92
SCHEMBL818308 0.85
SCHEMBL8359510 0.81 PTPN1 (0.31)
SCHEMBL5890412 0.80
SCHEMBL5889989 0.80
SCHEMBL5890809 0.80
SCHEMBL3697568 0.79 CNR1 (0.33)
SCHEMBL5890696 0.78 BCHE (0.30)
SCHEMBL5890821 0.78 CNR1 (0.33)
SCHEMBL5890563 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5912373-A Process for converting the achiral meso form of an ansa-metallocene complex into the chiral racemic form BASF AKTIENGESELLSCHAFT (DE) 1999-06-15 US disclosed
US-5892081-A REACTING TIN METALLOCENE WITH TRANSITION METAL HALIDE OR ALKOXIDE BASF AKTIENGESELLSCHAFT (DE) 1999-04-06 US disclosed
US-5840950-A Process for converting the achiral meso form or the racemate of an ansa-metallocene complex or mixtures thereof into one of its enantiomers BASF AKTIENGESELLSCHAFT (DE) 1998-11-24 US disclosed
CN-1190399-A Process for converting achiral meso form or racemate of ansa-metallocene complex or mixtures thereof into one of its enantiomers BASF AG (DE) 1998-08-12 CN disclosed