Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 20/20 | 0.69 |
| ▸ | F3 | P13726 | 9/20 | 0.45 |
| ▸ | F2 | P00734 | 5/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8362105 | 0.97 | F7 (0.74) | F7F3F2PRSS1 | |
| SCHEMBL8360220 | 0.96 | F7 (0.66) | F7F3F2PRSS1 | |
| SCHEMBL8363161 | 0.94 | F7 (0.64) | F7F3F2PRSS1 | |
| SCHEMBL8360266 | 0.93 | F7 (0.63) | F7F3F2PRSS1 | |
| SCHEMBL8360232 | 0.93 | F7 (0.63) | F7F3F2PRSS1 | |
| SCHEMBL8360104 | 0.92 | F7 (0.66) | F7F3F2PRSS1 | |
| SCHEMBL8363565 | 0.92 | F7 (0.61) | F7F3F2PRSS1 | |
| SCHEMBL8362336 | 0.92 | F7 (0.61) | F7F3F2PRSS1 | |
| SCHEMBL8362118 | 0.91 | F7 (0.62) | F7F3F2PRSS1 | |
| SCHEMBL8360333 | 0.91 | F7 (0.62) | F7F3F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028729-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |