Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 18/20 | 0.65 |
| ▸ | F3 | P13726 | 7/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 4/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6793117 | 0.90 | F7 (0.60) | F7F3PRSS1F2 | |
| SCHEMBL8360844 | 0.88 | F7 (0.67) | F7F3PRSS1F2 | |
| SCHEMBL8363577 | 0.87 | F7 (0.73) | F7F3PRSS1F2 | |
| SCHEMBL8360246 | 0.87 | F7 (0.73) | F7F3PRSS1F2 | |
| SCHEMBL8362597 | 0.86 | F7 (0.71) | F7F3PRSS1F2 | |
| SCHEMBL8363541 | 0.85 | F7 (0.66) | F7F3PRSS1F2 | |
| SCHEMBL8360173 | 0.85 | F7 (0.71) | F7F3PRSS1F2 | |
| SCHEMBL8360919 | 0.85 | F7 (0.68) | F7F3PRSS1F2 | |
| SCHEMBL8361853 | 0.84 | F7 (0.69) | F7F3PRSS1F2 | |
| SCHEMBL8361781 | 0.84 | F7 (0.69) | F7F3PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028729-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |