Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 10/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | F3 | P13726 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8360889 | 0.88 | F7 (0.39) | F7SCDAURKARPS6KB1 | |
| SCHEMBL8363696 | 0.87 | F7 (0.38) | F7AURKARPS6KB1 | |
| SCHEMBL8360318 | 0.87 | F7 (0.38) | F7AURKARPS6KB1 | |
| SCHEMBL6792414 | 0.86 | F7 (0.41) | F7SCDAURKARPS6KB1HDAC1 | |
| SCHEMBL6791082 | 0.84 | F2 (0.40) | F7SCDF2F3AURKA | |
| SCHEMBL8362513 | 0.84 | F7 (0.37) | F7 | |
| SCHEMBL8362598 | 0.83 | F7 (0.41) | F7SCDAURKARPS6KB1 | |
| SCHEMBL6798243 | 0.82 | F7 (0.40) | F7SCDF2F3AURKA | |
| SCHEMBL6798252 | 0.82 | F7 (0.40) | F7SCDF2F3AURKA | |
| SCHEMBL6791806 | 0.82 | F7 (0.40) | F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028729-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |