Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 20/20 | 0.83 |
| ▸ | F3 | P13726 | 8/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 3/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6794035 | 1.00 | F7 (0.83) | F7F3PRSS1F2PRSS2 | |
| SCHEMBL8363151 | 0.92 | F7 (0.75) | F7F3PRSS1F2PRSS2 | |
| SCHEMBL8360891 | 0.92 | F7 (0.75) | F7F3PRSS1F2PRSS2 | |
| SCHEMBL6790370 | 0.92 | F7 (0.75) | F7F3PRSS1F2PRSS2 | |
| SCHEMBL6790365 | 0.92 | F7 (0.75) | F7F3PRSS1F2PRSS2 | |
| SCHEMBL6790523 | 0.90 | F7 (0.73) | F7F3PRSS1F2PRSS2 | |
| SCHEMBL6647525 | 0.90 | F7 (0.70) | F7F3PRSS1F2PRSS2 | |
| SCHEMBL6650999 | 0.88 | F7 (0.73) | F7F3PRSS1F2PRSS2 | |
| SCHEMBL8360774 | 0.88 | F7 (0.69) | F7F3PRSS1F2 | |
| SCHEMBL6786242 | 0.87 | F7 (0.87) | F7F3PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028729-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |