Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 20/20 | 0.56 |
| ▸ | F3 | P13726 | 12/20 | 0.52 |
| ▸ | F2 | P00734 | 9/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8360238 | 0.94 | F7 (0.49) | F7F3F2F10PRSS1 | |
| SCHEMBL6790240 | 0.93 | F7 (0.50) | F7F3F2F10PRSS1 | |
| SCHEMBL8362107 | 0.93 | F7 (0.50) | F7F3F2F10PRSS1 | |
| SCHEMBL6790244 | 0.93 | F7 (0.50) | F7F3F2F10PRSS1 | |
| SCHEMBL8362336 | 0.92 | F7 (0.61) | F7F3F2F10PRSS1 | |
| SCHEMBL8363565 | 0.92 | F7 (0.61) | F7F3F2F10PRSS1 | |
| SCHEMBL8361943 | 0.91 | F7 (0.48) | F7F3F2F10PRSS1 | |
| SCHEMBL8360800 | 0.91 | F7 (0.48) | F7F3F2F10PRSS1 | |
| SCHEMBL8362044 | 0.90 | F7 (0.47) | F7F3F2F10PRSS1 | |
| SCHEMBL8362118 | 0.89 | F7 (0.62) | F7F3F2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028729-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |