Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 8/20 | 0.50 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL915680 | 0.90 | GALR3 (0.60) | GALR3HTR4KMT2AMAPTMEN1 | |
| SCHEMBL915682 | 0.90 | GALR3 (0.60) | GALR3HTR4KMT2AMAPTMEN1 | |
| SCHEMBL8360398 | 0.88 | CA1 (0.42) | GALR3HTR4KMT2AMEN1NPSR1 | |
| SCHEMBL5356411 | 0.85 | GALR3 (0.56) | GALR3HTR4KMT2AMAPTMEN1 | |
| SCHEMBL5356416 | 0.85 | GALR3 (0.56) | GALR3HTR4KMT2AMAPTMEN1 | |
| SCHEMBL5357199 | 0.85 | GALR3 (0.53) | GALR3HTR4KMT2AMAPTMEN1 | |
| SCHEMBL5357195 | 0.85 | GALR3 (0.53) | GALR3HTR4KMT2AMAPTMEN1 | |
| SCHEMBL8250410 | 0.82 | GALR3 (0.48) | GALR3HTR4KMT2AMAPTMEN1 | |
| SCHEMBL8171379 | 0.81 | GALR3 (0.58) | GALR3HTR4KMT2AMAPTMEN1 | |
| SCHEMBL6905755 | 0.81 | GALR3 (0.58) | GALR3HTR4KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014854-A1 | 3-IMINO-2-INDOLONES FOR THE TREATMENT OF DEPRESSION AND/OR ANXIETY | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2004-02-19 | — | — | WO | disclosed |