Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8362937 | 0.95 | ECE1 (0.68) | ECE1 | |
| SCHEMBL8360499 | 0.91 | ECE1 (0.63) | ECE1 | |
| SCHEMBL8338254 | 0.88 | ECE1 (0.78) | ECE1 | |
| SCHEMBL8362933 | 0.88 | ECE1 (0.64) | ECE1 | |
| SCHEMBL8360498 | 0.87 | ECE1 (0.65) | ECE1 | |
| SCHEMBL8361133 | 0.86 | ECE1 (0.60) | ECE1 | |
| SCHEMBL8363682 | 0.86 | ECE1 (0.64) | ECE1 | |
| SCHEMBL8334888 | 0.86 | ECE1 (0.64) | ECE1 | |
| SCHEMBL6020370 | 0.86 | ECE1 (1.00) | ECE1 | |
| SCHEMBL8363706 | 0.86 | ECE1 (0.79) | ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028719-A1 | SUBSTITUTED 2,5-DIAMIDOINDOLES AS ECE INHIBITORS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES | BAYER HEALTHCARE AG (DE) | 2003-04-10 | — | — | WO | disclosed |