Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 20/20 | 0.51 |
| ▸ | F3 | P13726 | 9/20 | 0.46 |
| ▸ | F2 | P00734 | 7/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8363693 | 0.93 | F7 (0.53) | F7F3F2PRSS1PRSS2 | |
| SCHEMBL8363446 | 0.90 | F7 (0.48) | F7F3F2PRSS1PRSS2 | |
| SCHEMBL8360800 | 0.90 | F7 (0.48) | F7F3F2PRSS1PRSS2 | |
| SCHEMBL8363343 | 0.89 | F7 (0.65) | F7F3F2PRSS1 | |
| SCHEMBL6793537 | 0.89 | F7 (0.52) | F7F3F2PRSS1PRSS2 | |
| SCHEMBL8360796 | 0.89 | F7 (0.52) | F7F3F2PRSS1PRSS2 | |
| SCHEMBL6793541 | 0.89 | F7 (0.52) | F7F3F2PRSS1PRSS2 | |
| SCHEMBL8363165 | 0.88 | F7 (0.63) | F7F3F2PRSS1PRSS2 | |
| SCHEMBL8360900 | 0.85 | F7 (0.56) | F7F3F2PRSS1PRSS2 | |
| SCHEMBL6791169 | 0.85 | F7 (0.64) | F7F3F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028729-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |