SCHEMBL8360973

SCHEMBL8360973

CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2C=O)c1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
C1S P09871 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4200893 0.90 C1S (0.70) C1S
SCHEMBL5840040 0.90 C1S (0.53) C1S
SCHEMBL5841108 0.89 C1S (0.63) C1S
SCHEMBL5839975 0.88 C1S (0.72) C1S
SCHEMBL5840012 0.88 C1S (0.54) C1S
SCHEMBL4207316 0.86 C1S (0.60) C1S
SCHEMBL5839752 0.86 C1S (0.56) C1S
SCHEMBL5841073 0.86 C1S (0.59) C1S
SCHEMBL5841057 0.85 C1S (0.59) C1S
SCHEMBL5840832 0.85 C1S (0.68) C1S

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003099805-A1 NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2003-12-04 WO disclosed