Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8361546 | 0.91 | PDE5A (1.00) | PDE5A | |
| SCHEMBL8360097 | 0.90 | PDE5A (1.00) | PDE5A | |
| SCHEMBL8358729 | 0.84 | PDE5A (1.00) | PDE5A | |
| SCHEMBL8221376 | 0.84 | PDE5A (0.73) | PDE5A | |
| SCHEMBL16298493 | 0.78 | PDE5A (0.76) | PDE5A | |
| SCHEMBL8358716 | 0.78 | PDE5A (1.00) | PDE5A | |
| SCHEMBL10201522 | 0.75 | PDE5A (0.61) | PDE5A | |
| SCHEMBL16298473 | 0.75 | PDE5A (1.00) | PDE5A | |
| SCHEMBL16297714 | 0.75 | PDE5A (0.73) | PDE5A | |
| SCHEMBL8360106 | 0.73 | PDE5A (0.68) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003042216-A1 | POLYCYCLIC GUANINE DERIVATIVE PHOSPHODIESTERASE V INHIBITORS | SCHERING CORPORATION (US) | 2003-05-22 | — | — | WO | disclosed |