Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 15/20 | 0.57 |
| ▸ | F3 | P13726 | 4/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8363209 | 0.86 | F7 (0.58) | F7F3PRSS1SYKF2 | |
| SCHEMBL6793924 | 0.86 | F7 (0.54) | F7F3 | |
| Hydrochloric Acid SCHEMBL6795206 | 0.85 | F7 (0.53) | F7F3 | |
| SCHEMBL8362430 | 0.83 | F7 (0.56) | F7F3PRSS1SYKF2 | |
| SCHEMBL6794047 | 0.83 | F7 (0.70) | F7F3PRSS1SYKF2 | |
| SCHEMBL8363217 | 0.82 | F7 (0.40) | F7F3PRSS1F2 | |
| SCHEMBL8363188 | 0.82 | F7 (0.55) | F7F3PRSS1SYKF2 | |
| SCHEMBL8363213 | 0.82 | F7 (0.57) | F7F3PRSS1SYK | |
| SCHEMBL6790727 | 0.81 | F7 (0.67) | F7F3PRSS1F2 | |
| SCHEMBL6796881 | 0.81 | F7 (0.49) | F7F3PRSS1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028729-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |