Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1S | P09871 | 20/20 | 1.00 |
| ▸ | F10 | P00742 | 1/20 | 0.63 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.63 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.63 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5842039 | 0.94 | C1S (0.89) | C1SF10PRSS1PRSS2PRSS3 | |
| SCHEMBL5840957 | 0.88 | C1S (0.78) | C1SF10PRSS1PRSS2PRSS3 | |
| SCHEMBL8363801 | 0.86 | C1S (1.00) | C1S | |
| SCHEMBL8361012 | 0.85 | C1S (1.00) | C1SF10PRSS1PRSS2PRSS3 | |
| SCHEMBL8360981 | 0.85 | C1S (1.00) | C1SF10PRSS1PRSS2PRSS3 | |
| SCHEMBL8361015 | 0.85 | C1S (1.00) | C1SF10PRSS1PRSS2PRSS3 | |
| SCHEMBL8361010 | 0.85 | C1S (1.00) | C1SF10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL5840663 | 0.81 | C1S (0.89) | C1S | |
| Trifluoroacetic Acid SCHEMBL5840070 | 0.81 | C1S (0.86) | C1SF10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL5841189 | 0.81 | C1S (0.90) | C1SF10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099805-A1 | NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2003-12-04 | — | — | WO | disclosed |