SCHEMBL8363603

SCHEMBL8363603

CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2cccc(C(O)C(F)(F)F)c2)c1

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
C1S P09871 20/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL5841816 0.96 C1S (0.68) C1S
Trifluoroacetic Acid SCHEMBL5840089 0.86 C1S (0.71) C1S
SCHEMBL5841823 0.85 C1S (0.64) C1S
SCHEMBL5840428 0.84 C1S (0.51) C1S
SCHEMBL8363749 0.84 C1S (1.00) C1S
SCHEMBL8363265 0.83 C1S (0.79) C1S
Trifluoroacetic Acid SCHEMBL5840658 0.83 C1S (0.86) C1S
Trifluoroacetic Acid SCHEMBL5840629 0.83 C1S (0.71) C1S
Trifluoroacetic Acid SCHEMBL5842250 0.83 C1S (0.84) C1S
SCHEMBL8363637 0.82 C1S (0.73) C1S

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003099805-A1 NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2003-12-04 WO disclosed