SCHEMBL8363648

SCHEMBL8363648

CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2C(=O)NCCCN2CCOCC2)c1

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
C1S P09871 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8363808 0.88 C1S (0.56) C1S
SCHEMBL6238531 0.85 C1S (0.47) C1S
SCHEMBL5841499 0.82 C1S (0.73) C1S
SCHEMBL8363773 0.80 C1S (0.69) C1S
SCHEMBL5840539 0.80 C1S (0.60) C1S
SCHEMBL5840910 0.78 C1S (1.00) C1S
Trifluoroacetic Acid SCHEMBL5841235 0.77 C1S (0.55) C1S
Trifluoroacetic Acid SCHEMBL5840253 0.76 C1S (0.63) C1S
SCHEMBL8363359 0.75 C1S (0.74) C1S
Trifluoroacetic Acid SCHEMBL5840109 0.74 C1S (0.80) C1S

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003099805-A1 NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2003-12-04 WO disclosed