Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CMA1 | P23946 | 2/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CTRC | Q99895 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38652097 | 0.92 | CMA1 (0.56) | ACECTSLFKBP1AKLK5CMA1 | |
| SCHEMBL21409190 | 0.92 | KLK5 (0.62) | ACEKLK5LMNACMA1F2 | |
| SCHEMBL21409192 | 0.92 | KLK5 (0.62) | ACEKLK5LMNACMA1F2 | |
| SCHEMBL21409191 | 0.92 | KLK5 (0.62) | ACEKLK5LMNACMA1F2 | |
| SCHEMBL1815101 | 0.91 | ACE (0.55) | ACECTSLFKBP1AKLK5CMA1 | |
| SCHEMBL7537159 | 0.91 | ACE (0.63) | ACECTSLFKBP1AKLK5CMA1 | |
| SCHEMBL10403794 | 0.91 | ACE (0.56) | ACECTSLFKBP1AKLK5CMA1 | |
| SCHEMBL7148899 | 0.91 | ACE (0.63) | ACECTSLFKBP1AKLK5CMA1 | |
| SCHEMBL10403621 | 0.90 | KLK7 (0.53) | ACECTSLFKBP1AKLK5CMA1 | |
| SCHEMBL38652049 | 0.90 | ACE (0.54) | ACECTSLFKBP1AKLK5CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057722-A2 | CYCLIC TETRAPEPTIDE COMPOUND AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-17 | — | — | WO | disclosed |