Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.65 |
| ▸ | ERBB2 | P04626 | 9/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8367350 | 0.92 | EGFR (0.73) | EGFRERBB2 | |
| SCHEMBL8361621 | 0.87 | EGFR (0.76) | EGFRERBB2 | |
| SCHEMBL8366126 | 0.87 | EGFR (0.79) | EGFRERBB2 | |
| SCHEMBL8365884 | 0.86 | EGFR (0.65) | EGFRERBB2 | |
| SCHEMBL8365916 | 0.85 | EGFR (0.71) | EGFRERBB2 | |
| SCHEMBL2102131 | 0.83 | EGFR (0.59) | EGFRERBB2 | |
| SCHEMBL2101368 | 0.82 | EGFR (0.57) | EGFRERBB2 | |
| SCHEMBL8361109 | 0.82 | EGFR (0.67) | EGFRERBB2 | |
| SCHEMBL8515985 | 0.82 | EGFR (0.72) | EGFRERBB2 | |
| SCHEMBL8367370 | 0.81 | EGFR (0.68) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999035132-A1 | HETEROCYCLIC COMPOUNDS | GLAXO GROUP LIMITED (GB) | 1999-07-15 | — | — | WO | disclosed |