SCHEMBL8364664

SCHEMBL8364664

O=C(O)C(=O)Nc1cc(N2CC(CNC(=O)c3ccc(Cl)s3)OC2=O)ccc1N1CCCCC1

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.73
F2 P00734 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL87232 0.91 F10 (0.75) F10
SCHEMBL87286 0.91 F10 (0.71) F10F2
SCHEMBL87353 0.90 F10 (0.73) F10F2
SCHEMBL87349 0.90 F10 (0.73) F10
SCHEMBL79151 0.90 F10 (0.76) F10
SCHEMBL87170 0.90 F10 (0.72) F10
SCHEMBL87284 0.90 F10 (0.72) F10
SCHEMBL87686 0.90 F10 (0.72) F10F2
SCHEMBL14641463 0.90 F10 (0.72) F10F2
SCHEMBL13479698 0.90 F10 (0.72) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003000256-A1 SUBSTITUTED OXAZOLIDINONES FOR COMBINATIONAL THERAPY BAYER HEALTHCARE AG (DE) 2003-01-03 WO disclosed