Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 18/20 | 0.60 |
| ▸ | BACE2 | Q9Y5Z0 | 7/20 | 0.60 |
| ▸ | CTSD | P07339 | 9/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8361163 | 0.92 | BACE1 (0.60) | BACE1BACE2CTSD | |
| SCHEMBL8361152 | 0.91 | BACE1 (0.64) | BACE1BACE2CTSD | |
| SCHEMBL5833473 | 0.89 | BACE1 (0.74) | BACE1BACE2CTSD | |
| SCHEMBL8362609 | 0.88 | BACE1 (0.57) | BACE1BACE2CTSD | |
| SCHEMBL5833876 | 0.87 | BACE1 (0.62) | BACE1BACE2CTSD | |
| SCHEMBL8365020 | 0.86 | BACE1 (0.58) | BACE1BACE2CTSD | |
| SCHEMBL8363993 | 0.86 | BACE1 (0.60) | BACE1BACE2CTSD | |
| SCHEMBL5832892 | 0.85 | BACE1 (0.75) | BACE1BACE2CTSD | |
| SCHEMBL6343440 | 0.84 | BACE1 (0.63) | BACE1BACE2CTSD | |
| SCHEMBL6355011 | 0.84 | BACE1 (0.63) | BACE1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006453-A1 | AMINEDIOLS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2003-01-23 | — | — | WO | disclosed |