Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Adenosine Phosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 4/20 | 0.76 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.76 |
| ▸ | SRC | P12931 | 2/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.76 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.76 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.76 |
| ▸ | LDHA | P00338 | 1/20 | 0.76 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.76 |
| ▸ | FBP1 | P09467 | 1/20 | 0.76 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.76 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.76 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.76 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.76 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.76 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.76 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.76 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.76 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.76 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine Phosphate SCHEMBL17144429 | 1.00 | P2RY1 (0.76) | P2RY1P2RY2SRCSMN1; SMN2DNPH1 | |
| Adenosine Phosphate SCHEMBL15670547 | 0.98 | P2RY1 (0.77) | P2RY1P2RY2SRCSMN1; SMN2DNPH1 | |
| Adenosine Phosphate SCHEMBL15670572 | 0.92 | P2RY1 (0.64) | P2RY1P2RY2SRCSMN1; SMN2DNPH1 | |
| Adenosine Phosphate SCHEMBL1331852 | 0.92 | P2RY1 (0.76) | P2RY1P2RY2SRCSMN1; SMN2DNPH1 | |
| Adenosine Phosphate SCHEMBL15670584 | 0.90 | P2RY1 (0.78) | P2RY1P2RY2SRCSMN1; SMN2DNPH1 | |
| Adenosine Phosphate SCHEMBL15670859 | 0.90 | P2RY1 (0.65) | P2RY1P2RY2SRCSMN1; SMN2DNPH1 | |
| SCHEMBL30151699 | 0.90 | P2RY1 (0.70) | P2RY1P2RY2SRCSMN1; SMN2DNPH1 | |
| Adenosine Phosphate SCHEMBL15670721 | 0.89 | P2RY1 (0.77) | P2RY1P2RY2SRCSMN1; SMN2DNPH1 | |
| Adenosine Phosphate SCHEMBL7225652 | 0.89 | P2RY1 (0.77) | P2RY1P2RY2SRCSMN1; SMN2DNPH1 | |
| Adenosine Phosphate SCHEMBL2406483 | 0.88 | P2RY1 (0.81) | P2RY1P2RY2SRCSMN1; SMN2DNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914132-A1 | FLAVOUR ADDITIVES | Mars, Incorporated (US) | 2015-09-09 | — | — | EP | disclosed |
| WO-2014068045-A1 | FLAVOUR ADDITIVES | MARS, INCORPORATED (US) | 2014-05-08 | — | — | WO | disclosed |
| EP-0954596-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF $i(TAXUS) SPECIES | PHYTON, INC. (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1997044476-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON, INC. (US) | 1997-11-27 | — | — | WO | disclosed |