Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | CMA1 | P23946 | 9/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5971091 | 0.86 | ACE (0.59) | ACEF2PRSS1KLK5CMA1 | |
| SCHEMBL17081787 | 0.84 | ACE (0.56) | ACEF2PRSS1KLK5CMA1 | |
| SCHEMBL10021917 | 0.84 | ACE (0.56) | ACEF2PRSS1KLK5CMA1 | |
| SCHEMBL10053455 | 0.84 | ACE (0.56) | ACEF2PRSS1KLK5CMA1 | |
| SCHEMBL7321218 | 0.82 | ACE (0.60) | ACEF2PRSS1KLK5CMA1 | |
| SCHEMBL28002552 | 0.81 | KLK5 (0.69) | ACEF2PRSS1KLK5CMA1 | |
| SCHEMBL7268512 | 0.81 | KLK5 (0.69) | ACEF2PRSS1KLK5CMA1 | |
| SCHEMBL28002546 | 0.81 | KLK5 (0.69) | ACEF2PRSS1KLK5CMA1 | |
| SCHEMBL12658455 | 0.81 | KLK5 (0.69) | ACEF2PRSS1KLK5CMA1 | |
| SCHEMBL8366819 | 0.79 | DPP4 (0.58) | ACEF2PRSS1KLK5OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057722-A2 | CYCLIC TETRAPEPTIDE COMPOUND AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-17 | — | — | WO | disclosed |