Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL722539 | 0.97 | PTGS1 (0.31) | PTGS1SLC7A11KDM4EMAPTTHRB | |
| SCHEMBL10711654 | 0.78 | — | — | |
| Potassium Ion SCHEMBL28427961 | 0.76 | — | — | |
| SCHEMBL449640 | 0.72 | — | — | |
| SCHEMBL268056 | 0.71 | ACE (0.31) | — | |
| SCHEMBL4854159 | 0.69 | — | — | |
| SCHEMBL10834897 | 0.69 | — | — | |
| SCHEMBL3983465 | 0.69 | — | — | |
| SCHEMBL487338 | 0.69 | — | — | |
| Ammonia Solution, Strong SCHEMBL10415819 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686203-A4 | COMPOUNDS AND METHODS FOR THE DIAGNOSIS, TREATMENT AND PREVENTION OF DISEASES OF CELL DEATH | GEN HOSPITAL CORP (US) | 1999-08-25 | — | — | EP | claimed |
| EP-0686203-A1 | COMPOUNDS AND METHODS FOR THE DIAGNOSIS, TREATMENT AND PREVENTION OF DISEASES OF CELL DEATH | THE GENERAL HOSPITAL CORPORATION (US) | 1995-12-13 | — | — | EP | claimed |
| WO-1994019493-A1 | COMPOUNDS AND METHODS FOR THE DIAGNOSIS, TREATMENT AND PREVENTION OF DISEASES OF CELL DEATH | THE GENERAL HOSPITAL CORPORATION (US) | 1994-09-01 | — | — | WO | claimed |
| EP-0678030-A1 | USE OF SULPHATED POLYSACCHARIDES FOR PREVENTING SEXUALLY TRANSMITTED DISEASES | THE POPULATION COUNCIL (US) | 1995-10-25 | — | — | EP | disclosed |
| WO-1994015624-A1 | USE OF SULPHATED POLYSACCHARIDES FOR PREVENTING SEXUALLY TRANSMITTED DISEASES | THE POPULATION COUNCIL (US) | 1994-07-21 | — | — | WO | disclosed |