Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.70 |
| ▸ | CASP2 | P42575 | 1/20 | 0.61 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.57 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.57 |
| ▸ | NAAA | Q02083 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 6/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL726184 | 1.00 | EPHX1 (0.70) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL9339993 | 1.00 | EPHX1 (0.70) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL27480377 | 1.00 | EPHX1 (0.70) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL5932906 | 1.00 | EPHX1 (0.70) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL79864 | 1.00 | EPHX1 (0.70) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL10437286 | 1.00 | EPHX1 (0.70) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL5932095 | 1.00 | EPHX1 (0.70) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL5932392 | 1.00 | EPHX1 (0.70) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL235545 | 0.97 | — | — | |
| SCHEMBL42438 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147768-B1 | GLYCERIN DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1989-02-08 | — | — | EP | claimed |
| US-4731373-A | BLOOD PLATELET ACTIVATING FACTOR | HOFFMAN-LA ROCHE INC. (US) | 1988-03-15 | — | — | US | claimed |
| EP-0208932-A2 | Glycerin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1987-01-21 | — | — | EP | claimed |
| EP-0147768-A2 | Glycerin derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-07-10 | — | — | EP | claimed |
| CN-112996519-A | Compositions and methods for organ-specific delivery of nucleic acids | 德克萨斯大学系统董事会 | 2021-06-18 | — | — | CN | disclosed |
| CN-112930198-A | Compositions and methods for organ-specific delivery of nucleic acids | 德克萨斯大学系统董事会 | 2021-06-08 | — | — | CN | disclosed |
| CN-101213266-A | Polyaspartic acid derivatives in covering agents containing polysiloxane | LANXESS DEUTSCHLAND GMBH (DE) | 2008-07-02 | — | — | CN | disclosed |
| WO-1999049865-A1 | USE OF PLATELET ACTIVATING FACTOR (PAF) INHIBITORS TO INHIBIT IL-5 INDUCED EOSINOPHIL ACTIVATION OR DEGRANULATION | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1999-10-07 | — | — | WO | disclosed |
| CN-1088199-A | The aniline that N-replaces | HOFFMANN LA ROCHE (CH) | 1994-06-22 | — | — | CN | disclosed |
| US-5187293-A | Blood platelet activating factor inhibitors | HOFFMANN-LA ROCHE INC. (US) | 1993-02-16 | — | — | US | disclosed |
| US-5057530-A | For inhibiting blood platelet activating faactors | HOFFMANN-LA ROCHE INC. (US) | 1991-10-15 | — | — | US | disclosed |
| US-4863941-A | PLATELET ACTIVATING FACTOR INHIBITORS, ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0147768-B1 | GLYCERIN DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1989-02-08 | — | — | EP | disclosed |
| US-4732845-A | COLORLESS PHENOLIC AMIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1988-03-22 | — | — | US | disclosed |
| US-4731373-A | BLOOD PLATELET ACTIVATING FACTOR | HOFFMAN-LA ROCHE INC. (US) | 1988-03-15 | — | — | US | disclosed |
| EP-0250723-A2 | Silver halide color photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1988-01-07 | — | — | EP | disclosed |
| EP-0208932-A2 | Glycerin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1987-01-21 | — | — | EP | disclosed |
| EP-0147768-A2 | Glycerin derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-07-10 | — | — | EP | disclosed |
| US-4191574-A | AZO-METHINE DYES | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1980-03-04 | — | — | US | disclosed |