Sugi Predict

Sugi Predict / Compounds / SCHEMBL8367272

SCHEMBL8367272

SCHEMBL8367272

CS(=O)(=O)CCNCCCOc1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ EGFR P00533 16/20 1.00
▸ ERBB2 P04626 15/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8363439 0.97 EGFR (1.00) EGFRERBB2
SCHEMBL8362574 0.97 EGFR (0.95) EGFRERBB2
SCHEMBL8368189 0.93 EGFR (0.87) EGFRERBB2
SCHEMBL8367607 0.90 EGFR (0.82) EGFRERBB2
SCHEMBL8364230 0.90 EGFR (0.84) EGFRERBB2
SCHEMBL8361791 0.90 EGFR (0.82) EGFRERBB2
SCHEMBL8361665 0.90 EGFR (0.87) EGFRERBB2
SCHEMBL8367271 0.90 EGFR (0.82) EGFRERBB2
SCHEMBL8364155 0.90 EGFR (0.83) EGFRERBB2
SCHEMBL8365878 0.89 EGFR (0.80) EGFRERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999035132-A1 HETEROCYCLIC COMPOUNDS GLAXO GROUP LIMITED (GB) 1999-07-15 — — WO claimed
WO-1999035132-A1 HETEROCYCLIC COMPOUNDS GLAXO GROUP LIMITED (GB) 1999-07-15 — — WO disclosed