Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 18/20 | 0.57 |
| ▸ | BACE2 | Q9Y5Z0 | 7/20 | 0.57 |
| ▸ | APP | P05067 | 4/20 | 0.51 |
| ▸ | CTSD | P07339 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6294087 | 0.92 | BACE1 (0.57) | BACE1BACE2APPCTSDGAA | |
| SCHEMBL6298730 | 0.92 | BACE1 (0.57) | BACE1BACE2APPCTSDGAA | |
| SCHEMBL6298729 | 0.92 | BACE1 (0.57) | BACE1BACE2APPCTSDGAA | |
| SCHEMBL6295359 | 0.89 | BACE1 (0.59) | BACE1BACE2APPCTSD | |
| SCHEMBL6298866 | 0.87 | BACE1 (0.52) | BACE1BACE2APPCTSD | |
| SCHEMBL6294127 | 0.87 | BACE1 (0.71) | BACE1BACE2APPCTSD | |
| SCHEMBL6294154 | 0.81 | BACE1 (0.66) | BACE1BACE2APPCTSD | |
| SCHEMBL8367140 | 0.79 | BACE1 (0.80) | BACE1BACE2 | |
| Hydrochloric Acid SCHEMBL6295174 | 0.79 | BACE1 (0.79) | BACE1BACE2 | |
| SCHEMBL14136382 | 0.78 | BACE1 (0.82) | BACE1BACE2APPCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057721-A2 | SUBSTITUTED AMINO CARBOXAMIDES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2003-07-17 | — | — | WO | disclosed |