Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dichlororibobenzimidazole SCHEMBL29352589 | 1.00 | TP53 (0.54) | TP53LMNAKDM4EPKMHDAC6 | |
| Dichlororibobenzimidazole SCHEMBL1535249 | 1.00 | TP53 (0.54) | TP53LMNAKDM4EPKMHDAC6 | |
| Dichlororibobenzimidazole SCHEMBL8368991 | 1.00 | TP53 (0.54) | TP53LMNAKDM4EPKMHDAC6 | |
| Dichlororibobenzimidazole SCHEMBL23815679 | 1.00 | TP53 (0.54) | TP53LMNAKDM4EPKMHDAC6 | |
| Dichlororibobenzimidazole SCHEMBL362387 | 1.00 | TP53 (0.54) | TP53LMNAKDM4EPKMHDAC6 | |
| Dichlororibobenzimidazole SCHEMBL23982247 | 1.00 | TP53 (0.54) | TP53LMNAKDM4EPKMHDAC6 | |
| Dichlororibobenzimidazole SCHEMBL7812697 | 1.00 | TP53 (0.54) | TP53LMNAKDM4EPKMHDAC6 | |
| Dichlororibobenzimidazole SCHEMBL20419020 | 1.00 | TP53 (0.54) | TP53LMNAKDM4EPKMHDAC6 | |
| Dichlororibobenzimidazole SCHEMBL8368931 | 1.00 | TP53 (0.54) | TP53LMNAKDM4EPKMHDAC6 | |
| Dichlororibobenzimidazole SCHEMBL29533962 | 1.00 | TP53 (0.54) | TP53LMNAKDM4EPKMHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999051619-A1 | ARABINOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1999-10-14 | — | — | WO | claimed |