SCHEMBL8367491

SCHEMBL8367491

CC(C)(c1ccccc1)c1ccc(-c2ccccc2)c(S(=O)(=O)O)c1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 4/20 0.39
CNR2 P34972 4/20 0.39
ESR2 Q92731 2/20 0.38
ALDH1A1 P00352 1/20 0.38
ESR1 P03372 1/20 0.38
CYP3A4 P08684 1/20 0.38
NR3C2 P08235 3/20 0.35
PTPN1 P18031 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
PTPN5 P54829 1/20 0.33
DAPK1 P53355 1/20 0.33
ACLY P53396 1/20 0.32
CYP2D6 P10635 1/20 0.32
PTGS2 P35354 1/20 0.32
PDE4A P27815 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE4C Q08493 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8365871 0.84 ESR1 (0.41) CNR1CNR2ESR2ALDH1A1ESR1
SCHEMBL8369543 0.82 ESR1 (0.40) CNR1CNR2ESR2ALDH1A1ESR1
SCHEMBL8369552 0.80 ESR1 (0.43) CNR1CNR2ESR2ALDH1A1ESR1
SCHEMBL8365868 0.80 CNR1 (0.40) CNR1CNR2ESR2ALDH1A1ESR1
SCHEMBL8365842 0.78 CNR1 (0.40) CNR1CNR2ESR2ALDH1A1ESR1
SCHEMBL8368892 0.78 ESR1 (0.41) CNR1CNR2ESR2ALDH1A1ESR1
SCHEMBL8370458 0.77 CYP2D6 (0.41) ESR2ALDH1A1PTPN1HDAC4HDAC2
SCHEMBL9249621 0.77 GLRA3 (0.41) CNR1CNR2ESR2ALDH1A1ESR1
SCHEMBL8365847 0.76 CNR1 (0.38) CNR1CNR2ESR2ALDH1A1ESR1
SCHEMBL8367507 0.76 CNR1 (0.39) CNR1CNR2ESR2ALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed