Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 1.00 |
| ▸ | F10 | P00742 | 4/20 | 0.80 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4427568 | 1.00 | F2 (1.00) | F2F10PRSS1 | |
| SCHEMBL8368342 | 0.89 | F2 (1.00) | F2F10PRSS1 | |
| SCHEMBL4427616 | 0.89 | F2 (1.00) | F2F10PRSS1 | |
| SCHEMBL4430767 | 0.86 | F2 (0.77) | F2F10PRSS1 | |
| SCHEMBL4425042 | 0.86 | F2 (1.00) | F2F10PRSS1 | |
| SCHEMBL13885804 | 0.84 | F2 (0.82) | F2F10PRSS1 | |
| SCHEMBL4427676 | 0.81 | F2 (1.00) | F2F10PRSS1 | |
| SCHEMBL4420643 | 0.77 | F2 (0.65) | F2F10PRSS1 | |
| SCHEMBL13885807 | 0.76 | F2 (0.69) | F2F10PRSS1 | |
| SCHEMBL4427640 | 0.74 | F2 (0.76) | F2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524871-B2 | Thrombin inhibitors | UNIVERSITY OF LJUBLJANA, FACULTY OF PHARMACY (SI) | 2009-04-28 | — | — | US | disclosed |
| US-7524871-B2 | Thrombin inhibitors | UNIVERSITY OF LJUBLJANA, FACULTY OF PHARMACY (SI) | 2009-04-28 | — | — | US | disclosed |
| WO-2003048155-A1 | THROMBIN INHIBITORS | UNIVERSITY OF LJUBLJANA (SI) | 2003-06-12 | — | — | WO | disclosed |