Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.59 |
| ▸ | F10 | P00742 | 2/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4431628 | 0.91 | F2 (0.58) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL8366491 | 0.88 | F2 (0.56) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL4421155 | 0.87 | F2 (0.57) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL8366434 | 0.84 | F2 (0.74) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL14131869 | 0.84 | F2 (0.56) | F2F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL5124376 | 0.81 | F2 (0.54) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL8367660 | 0.80 | ATM (0.44) | F2F10PRSS1 | |
| SCHEMBL4427658 | 0.79 | F2 (0.60) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL13885838 | 0.76 | F2 (1.00) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL4422054 | 0.76 | F2 (1.00) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524871-B2 | Thrombin inhibitors | UNIVERSITY OF LJUBLJANA, FACULTY OF PHARMACY (SI) | 2009-04-28 | — | — | US | disclosed |
| WO-2003048155-A1 | THROMBIN INHIBITORS | UNIVERSITY OF LJUBLJANA (SI) | 2003-06-12 | — | — | WO | disclosed |