Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8368273

C=C(C)C(=O)OC(C)OS(=O)(=O)CCC.N

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
THRB P10828 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29154934 0.98 TSHR (0.38) TSHRTHRBALDH1A1
SCHEMBL28192294 0.83 TSHR (0.36) TSHRTHRBALDH1A1
Ammonia Solution, Strong SCHEMBL145161 0.78 TSHR (0.38) TSHRALDH1A1
Ammonia Solution, Strong SCHEMBL8370318 0.77 TSHR (0.37) TSHRTHRB
SCHEMBL5906415 0.77 TSHR (0.41) TSHRTHRBALDH1A1
SCHEMBL167768 0.75 TSHR (0.39) TSHRALDH1A1
Ammonia Solution, Strong SCHEMBL23359172 0.75
SCHEMBL5872176 0.75 TSHR (0.40) TSHRTHRBALDH1A1
Ammonia Solution, Strong SCHEMBL27806401 0.74 TSHR (0.37) TSHRTHRBALDH1A1
SCHEMBL22232690 0.74 TSHR (0.34) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9757330-B2 Recipe for in-situ gel, and implant, drug delivery system formed thereby INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-09-12 US claimed
EP-0888401-A1 CONDUCTIVE ADHESIVES PREPARED FROM ZWITTERIONIC MATERIALS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-01-07 EP claimed
US-5846558-A Ionically conductive adhesives prepared from zwitterionic materials and medical devices using such adhesives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-12-08 US claimed
WO-1997034947-A1 CONDUCTIVE ADHESIVES PREPARED FROM ZWITTERIONIC MATERIALS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-25 WO claimed
CN-104548117-B In situ gel formulation, implant and drug delivery system 财团法人工业技术研究院 2018-11-20 CN disclosed
CN-104548117-A In situ gel formulation, implant and drug delivery system IND TECH RES INST 2015-04-29 CN disclosed
CN-1214062-A Conductive adhesive prepared from zwitterionic materials MINNESOTA MINING & MFG (US) 1999-04-14 CN disclosed
EP-0888401-A1 CONDUCTIVE ADHESIVES PREPARED FROM ZWITTERIONIC MATERIALS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-01-07 EP disclosed
US-5846558-A Ionically conductive adhesives prepared from zwitterionic materials and medical devices using such adhesives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-12-08 US disclosed
WO-1997034947-A1 CONDUCTIVE ADHESIVES PREPARED FROM ZWITTERIONIC MATERIALS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-25 WO disclosed