⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11687264 | 0.96 | — | — | |
| SCHEMBL17028873 | 0.96 | TSHR (0.58) | — | |
| SCHEMBL16933 | 0.96 | — | — | |
| SCHEMBL11047830 | 0.92 | — | — | |
| Monoethanolamine SCHEMBL6884057 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL4345953 | 0.92 | — | — | |
| Water SCHEMBL5930812 | 0.92 | — | — | |
| Water SCHEMBL10698036 | 0.92 | — | — | |
| SCHEMBL11561593 | 0.92 | — | — | |
| Bromide SCHEMBL5998898 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3350170-B1 | HETEROARYL COMPOUNDS AS IRAK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2022-01-26 | — | — | EP | disclosed |
| US-20220010236-A1 | LIQUID DETERGENT COMPOSITION | THE PROCTER AND GAMBLE COMPANY | 2022-01-13 | — | — | US | disclosed |
| CN-108602776-B | Heteroaryl compounds as IRAK inhibitors and uses thereof | 默克专利有限公司 | 2021-12-03 | — | — | CN | disclosed |
| US-20190233782-A1 | UNITARY LAUNDRY DETERGENT ARTICLE HAVING FIBROUS SUBSTRATES | THE PROCTER AND GAMBLE COMPANY | 2019-08-01 | — | — | US | disclosed |
| US-20180237413-A1 | HETEROARYL COMPOUNDS AS IRAK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2018-08-23 | — | — | US | disclosed |
| EP-3350170-A1 | HETEROARYL COMPOUNDS AS IRAK INHIBITORS AND USES THEREOF | Merck Patent GmbH (DE) | 2018-07-25 | — | — | EP | disclosed |
| US-9969710-B2 | Heteroaryl compounds as IRAK inhibitors and uses thereof | MERCK PATENT GMBH (DE) | 2018-05-15 | — | — | US | disclosed |
| WO-2017049069-A1 | HETEROARYL COMPOUNDS AS IRAK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-03-23 | — | — | WO | disclosed |
| US-20170081307-A1 | HETEROARYL COMPOUNDS AS IRAK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-03-23 | — | — | US | disclosed |
| CN-102811776-B | Surfactant compositions from polyfluoroalkylsulfonamido alkyl amines | DU PONT | 2015-06-24 | — | — | CN | disclosed |
| CN-102844298-B | Mixture of polyfluoroalkylsulfonamido alkyl amines | DU PONT | 2015-01-14 | — | — | CN | disclosed |
| CN-102822144-B | Polyfluoroalkylsulfinamidoalkyl halide intermediate | DU PONT | 2014-12-31 | — | — | CN | disclosed |
| US-6004719-A | ACID-GENERATING LAYER OR PHASE COMPRISING A MIXTURE OF A SUPERACID PRECURSOR, A SENSITIZING DYE AND A SECONDARY ACID GENERATOR, AND A COLOR-CHANGE LAYER OR PHASE COMPRISING AN IMAGE DYE. | POLAROID CORPORATION (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0757629-B1 | IMAGING MEDIUM AND PROCESS | POLAROID CORP (US) | 1999-01-20 | — | — | EP | disclosed |
| US-5631118-A | MULTILAYER ELEMENT WITH ACID GENERATING LAYER, ACID PRECURSOR, SENSITIZING DYE, ACID GENERATOR AND COLOR CHANGING LAYER | POLAROID CORPORATION (US) | 1997-05-20 | — | — | US | disclosed |
| EP-0757629-A1 | IMAGING MEDIUM AND PROCESS | POLAROID CORPORATION (US) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029068-A1 | IMAGING MEDIUM AND PROCESS | POLAROID CORPORATION (US) | 1995-11-02 | — | — | WO | disclosed |