Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 3/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.49 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.49 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.49 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8367770 | 0.87 | GRIN2D (0.40) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL8365182 | 0.87 | GRIA1 (0.40) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL8368402 | 0.87 | GRIA1 (0.39) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL8368460 | 0.84 | GRIN2D (0.53) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL8364546 | 0.79 | GRIA1 (0.43) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL8364708 | 0.79 | GRIN2D (0.39) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL8195327 | 0.79 | GRIA1 (0.39) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL8186918 | 0.76 | KDM4E (0.37) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL9080503 | 0.74 | GRIN2D (0.48) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL8364711 | 0.73 | GRIA1 (0.38) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001832-A | [1,2,4]triazolo[4,3-a]quinoxalinone derivatives, their preparation and use | NOVO NORDISKALS (DK) | 1999-12-14 | — | — | US | disclosed |
| EP-0783504-A1 | [1,2,4]TRIAZOLO[4,3-a]QUINOXALINONE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996008492-A1 | [1,2,4]TRIAZOLO[4,3-a]QUINOXALINONE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1996-03-21 | — | — | WO | disclosed |