Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.47 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368492 | 1.00 | HIF1A (0.47) | HIF1ACLCN2TP53HTTMRGPRX4 | |
| SCHEMBL8396083 | 0.87 | HTT (0.57) | HIF1ATP53HTTMRGPRX4KMT2A | |
| SCHEMBL8372411 | 0.87 | HTT (0.57) | HIF1ATP53HTTMRGPRX4KMT2A | |
| SCHEMBL8372410 | 0.87 | HTT (0.57) | HIF1ATP53HTTMRGPRX4KMT2A | |
| SCHEMBL8369597 | 0.86 | HIF1A (0.51) | HIF1ACLCN2TP53HTTMRGPRX4 | |
| SCHEMBL8369599 | 0.86 | HIF1A (0.51) | HIF1ACLCN2TP53HTTMRGPRX4 | |
| SCHEMBL8371588 | 0.85 | MRGPRX4 (0.61) | HIF1ATP53HTTMRGPRX4TSHR | |
| SCHEMBL6452979 | 0.85 | MRGPRX4 (0.61) | HIF1ATP53HTTMRGPRX4TSHR | |
| SCHEMBL8371706 | 0.85 | HIF1A (0.53) | HIF1ATP53HTTMRGPRX4HDAC8 | |
| SCHEMBL6452972 | 0.85 | MRGPRX4 (0.61) | HIF1ATP53HTTMRGPRX4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617011-B1 | Process for producing alkoxyiminoacetamide compounds | SHIONOGI & CO (JP) | 1999-01-20 | — | — | EP | disclosed |
| EP-0617011-A2 | Process for producing alkoxyiminoacetamide compounds | SHIONOGI & CO., LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |