Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954782 | 1.00 | BRD4 (0.41) | BRD4HIF1ACYP2D6TSHREDNRA | |
| SCHEMBL9089339 | 1.00 | BRD4 (0.41) | BRD4HIF1ACYP2D6TSHREDNRA | |
| SCHEMBL8954733 | 1.00 | BRD4 (0.41) | BRD4HIF1ACYP2D6TSHREDNRA | |
| SCHEMBL8459950 | 0.79 | KAT2B (0.35) | BRD4HIF1APOLBKDM4EATM | |
| SCHEMBL8450635 | 0.79 | KAT2B (0.35) | BRD4HIF1APOLBKDM4EATM | |
| SCHEMBL8462177 | 0.79 | KAT2B (0.35) | BRD4HIF1APOLBKDM4EATM | |
| SCHEMBL8463919 | 0.77 | KDM4E (0.36) | BRD4HIF1AKDM4EATMALDH1A1 | |
| SCHEMBL8463915 | 0.77 | KDM4E (0.36) | BRD4HIF1AKDM4EATMALDH1A1 | |
| SCHEMBL8372501 | 0.74 | AKR1C3 (0.47) | HIF1ACYP2D6TSHRPOLBKDM4E | |
| SCHEMBL8372505 | 0.74 | AKR1C3 (0.47) | HIF1ACYP2D6TSHRPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617011-B1 | Process for producing alkoxyiminoacetamide compounds | SHIONOGI & CO (JP) | 1999-01-20 | — | — | EP | disclosed |
| US-5506358-A | USEFUL AS AGRICULTURAL FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0617011-A2 | Process for producing alkoxyiminoacetamide compounds | SHIONOGI & CO., LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |