Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6488098 | 0.82 | KDM4E (0.59) | KMT2AMEN1KDM4E | |
| SCHEMBL6488102 | 0.82 | KDM4E (0.59) | KMT2AMEN1KDM4E | |
| SCHEMBL6488092 | 0.82 | KDM4E (0.59) | KMT2AMEN1KDM4E | |
| SCHEMBL6476988 | 0.73 | KMT2A (0.68) | KMT2AMEN1KDM4E | |
| SCHEMBL7048394 | 0.69 | KMT2A (0.54) | KMT2AMEN1KDM4E | |
| SCHEMBL3865953 | 0.69 | KMT2A (0.54) | KMT2AMEN1KDM4E | |
| SCHEMBL7048398 | 0.69 | KMT2A (0.54) | KMT2AMEN1KDM4E | |
| SCHEMBL7048396 | 0.69 | KMT2A (0.54) | KMT2AMEN1KDM4E | |
| SCHEMBL19721184 | 0.68 | KDM4E (0.51) | KMT2AMEN1KDM4E | |
| SCHEMBL6485267 | 0.67 | PDPK1 (0.53) | KMT2AMEN1KDM4EPARP10PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003014116-A1 | PYRROLO[2.1-A]ISOQUINOLINE DERIVATIVES | BAYER CORPORATION (US) | 2003-02-20 | — | — | WO | disclosed |