Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.63 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.53 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.52 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371719 | 0.84 | MAPT (0.60) | MEN1KMT2ALMNAMAPTPOLB | |
| SCHEMBL7734705 | 0.82 | MAPK1 (0.74) | MEN1KMT2ALMNAALOX15MAPK1 | |
| SCHEMBL29373364 | 0.81 | MEN1 (0.61) | MEN1KMT2AMAPTCHRNA7ALOX15 | |
| SCHEMBL1850010 | 0.79 | MEN1 (0.68) | MEN1KMT2ALMNAMAPTKCNQ2 | |
| SCHEMBL826590 | 0.79 | MEN1 (0.61) | MEN1KMT2ALMNAMAPTKCNQ2 | |
| SCHEMBL825921 | 0.78 | MEN1 (0.59) | MEN1KMT2ALMNAMAPTKCNQ2 | |
| SCHEMBL1853620 | 0.78 | MEN1 (0.62) | MEN1KMT2ALMNAMAPTKCNQ2 | |
| SCHEMBL1463468 | 0.78 | NTRK1 (1.00) | NTRK1CDK19MEN1KMT2AMAPT | |
| SCHEMBL29763181 | 0.78 | NTRK1 (1.00) | NTRK1CDK19MEN1KMT2AMAPT | |
| SCHEMBL31240786 | 0.77 | RIOK2 (0.62) | MEN1KMT2ALMNAMAPTKCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693053-B1 | UREA AND AMIDE DERIVATIVES AND THEIR USE IN THE CONTROL OF CELL MEMBRANE POTASSIUM CHANNELS | NEUROSEARCH AS (DK) | 1999-01-20 | — | — | EP | claimed |
| US-5696138-A | Urea derivatives and their use | NEUROSEARCH A/S (DK) | 1997-12-09 | — | — | US | claimed |
| EP-0693053-A1 | UREA AND AMIDE DERIVATIVES AND THEIR USE IN THE CONTROL OF CELL MEMBRANE POTASSIUM CHANNELS | NEUROSEARCH A/S (DK) | 1996-01-24 | — | — | EP | claimed |
| WO-1994022807-A1 | UREA AND AMIDE DERIVATIVES AND THEIR USE IN THE CONTROL OF CELL MEMBRANE POTASSIUM CHANNELS | NEUROSEARCH A/S (DK) | 1994-10-13 | — | — | WO | claimed |
| EP-0910358-A1 | PHENYL DERIVATIVES USEFUL AS BLOCKERS OF CHLORIDE CHANNELS | NEUROSEARCH A/S (DK) | 1999-04-28 | — | — | EP | disclosed |
| EP-0693053-B1 | UREA AND AMIDE DERIVATIVES AND THEIR USE IN THE CONTROL OF CELL MEMBRANE POTASSIUM CHANNELS | NEUROSEARCH AS (DK) | 1999-01-20 | — | — | EP | disclosed |
| US-5696138-A | Urea derivatives and their use | NEUROSEARCH A/S (DK) | 1997-12-09 | — | — | US | disclosed |
| WO-1997045111-A1 | PHENYL DERIVATIVES USEFUL AS BLOCKERS OF CHLORIDE CHANNELS | NEUROSEARCH A/S (DK) | 1997-12-04 | — | — | WO | disclosed |
| EP-0693053-A1 | UREA AND AMIDE DERIVATIVES AND THEIR USE IN THE CONTROL OF CELL MEMBRANE POTASSIUM CHANNELS | NEUROSEARCH A/S (DK) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994022807-A1 | UREA AND AMIDE DERIVATIVES AND THEIR USE IN THE CONTROL OF CELL MEMBRANE POTASSIUM CHANNELS | NEUROSEARCH A/S (DK) | 1994-10-13 | — | — | WO | disclosed |