Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.70 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | GRIK1 | P39086 | 7/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | KIF11 | P52732 | 1/20 | 0.57 |
| ▸ | IDH2 | P48735 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 2/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5476438 | 0.90 | MEN1 (0.67) | NTRK1CDK19MEN1KMT2AMAPT | |
| SCHEMBL1462981 | 0.87 | NTRK1 (0.81) | NTRK1CDK19MEN1KMT2AMAPT | |
| SCHEMBL10217915 | 0.87 | KMT2A (0.88) | MEN1KMT2AMAPTHTTRAB9A | |
| SCHEMBL7556107 | 0.85 | NTRK1 (0.70) | NTRK1CDK19MEN1KMT2AMAPT | |
| SCHEMBL1463407 | 0.85 | NTRK1 (0.77) | NTRK1CDK19MEN1KMT2AMAPT | |
| SCHEMBL1463167 | 0.84 | KDR (0.73) | NTRK1CDK19MEN1KMT2AMAPT | |
| SCHEMBL8368351 | 0.84 | RXFP1 (0.62) | MEN1KMT2AMAPTHTTRAB9A | |
| SCHEMBL28317079 | 0.83 | IDH2 (0.70) | MEN1KMT2AMAPTHTTRAB9A | |
| SCHEMBL1463169 | 0.82 | GRIK1 (0.74) | NTRK1CDK19MEN1KMT2AMAPT | |
| SCHEMBL29763181 | 0.82 | NTRK1 (1.00) | NTRK1CDK19MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693053-B1 | UREA AND AMIDE DERIVATIVES AND THEIR USE IN THE CONTROL OF CELL MEMBRANE POTASSIUM CHANNELS | NEUROSEARCH AS (DK) | 1999-01-20 | — | — | EP | disclosed |
| US-5696138-A | Urea derivatives and their use | NEUROSEARCH A/S (DK) | 1997-12-09 | — | — | US | disclosed |
| EP-0693053-A1 | UREA AND AMIDE DERIVATIVES AND THEIR USE IN THE CONTROL OF CELL MEMBRANE POTASSIUM CHANNELS | NEUROSEARCH A/S (DK) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994022807-A1 | UREA AND AMIDE DERIVATIVES AND THEIR USE IN THE CONTROL OF CELL MEMBRANE POTASSIUM CHANNELS | NEUROSEARCH A/S (DK) | 1994-10-13 | — | — | WO | disclosed |