Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9415813 | 1.00 | HIF1A (0.45) | HIF1ASMN1; SMN2MEN1KMT2AMAPK8 | |
| SCHEMBL8372516 | 0.87 | HIF1A (0.48) | HIF1ASMN1; SMN2MAPTTDP1ALDH1A1 | |
| SCHEMBL8372515 | 0.87 | HIF1A (0.48) | HIF1ASMN1; SMN2MAPTTDP1ALDH1A1 | |
| SCHEMBL8398967 | 0.87 | HIF1A (0.53) | HIF1AMEN1KMT2AMAPTTDP1 | |
| SCHEMBL8372750 | 0.87 | HIF1A (0.53) | HIF1AMEN1KMT2AMAPTTDP1 | |
| SCHEMBL8372751 | 0.87 | HIF1A (0.53) | HIF1AMEN1KMT2AMAPTTDP1 | |
| SCHEMBL8368249 | 0.84 | HIF1A (0.50) | HIF1AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8368251 | 0.84 | HIF1A (0.50) | HIF1AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8372666 | 0.83 | HIF1A (0.51) | HIF1AMEN1KMT2AMAPTATM | |
| SCHEMBL8372663 | 0.83 | HIF1A (0.51) | HIF1AMEN1KMT2AMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617011-B1 | Process for producing alkoxyiminoacetamide compounds | SHIONOGI & CO (JP) | 1999-01-20 | — | — | EP | disclosed |
| US-5506358-A | USEFUL AS AGRICULTURAL FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0617011-A2 | Process for producing alkoxyiminoacetamide compounds | SHIONOGI & CO., LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |