Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | RAD52 | P43351 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22664061 | 0.88 | CXCR4 (0.47) | ANPEPERAP2SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL1408746 | 0.82 | SMN1; SMN2 (0.45) | ANPEPERAP2SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL1469940 | 0.82 | POLB (0.45) | ANPEPERAP2SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL9801548 | 0.80 | SMN1; SMN2 (0.46) | ANPEPERAP2SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL22320733 | 0.80 | SMN1; SMN2 (0.46) | ANPEPERAP2SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL9329894 | 0.80 | SMN1; SMN2 (0.43) | ANPEPERAP2SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL28303412 | 0.79 | SMN1; SMN2 (0.39) | ANPEPERAP2SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL3387998 | 0.78 | SMN1; SMN2 (0.42) | ANPEPERAP2SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL2267331 | 0.78 | ANPEP (0.44) | ANPEPERAP2SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL2267325 | 0.78 | ANPEP (0.44) | ANPEPERAP2SMN1; SMN2POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11005786-A | — | — | None | — | — | JP | disclosed |
| JP-H115786-A | NOVEL AMINOHYDROXYPROPYLPIPERAZINE DERIVATIVE | POLA CHEM IND INC | 1999-01-12 | — | — | JP | disclosed |