Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128952 | 0.71 | TSHR (0.30) | — | |
| SCHEMBL28880256 | 0.68 | CYP3A4 (0.42) | APEX1CYP3A4ALDH1A1ADORA2BPDE4A | |
| SCHEMBL29128953 | 0.67 | HTT (0.33) | ALDH1A1ADORA2BPDE4AADORA2APDE4B | |
| SCHEMBL3454101 | 0.67 | — | — | |
| SCHEMBL25014061 | 0.66 | CYP3A4 (0.50) | APEX1CYP3A4ALDH1A1ADORA2BPDE4A | |
| SCHEMBL11003768 | 0.65 | — | — | |
| SCHEMBL1560781 | 0.64 | CYP3A4 (0.54) | APEX1CYP3A4ALDH1A1ADORA2BPDE4A | |
| SCHEMBL20718876 | 0.64 | — | — | |
| SCHEMBL8420872 | 0.64 | CYP3A4 (0.48) | CYP3A4ALDH1A1ADORA2BPDE4AADORA2A | |
| SCHEMBL157928 | 0.63 | CYP3A4 (0.71) | APEX1CYP3A4ALDH1A1ADORA2BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11012544-A | — | — | None | — | — | JP | disclosed |
| JP-H1112544-A | PRIMER COMPOSITION | NIPPON KASEI CHEM CO LTD | 1999-01-19 | — | — | JP | disclosed |