SCHEMBL8370831

SCHEMBL8370831

CCOC(=O)OC(=O)C(C)(C)C

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 1/20 0.64
ALDH1A1 P00352 3/20 0.55
LMNA P02545 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PKM P14618 3/20 0.39
KDM4E B2RXH2 1/20 0.39
ALOX15 P16050 1/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
CYP4F2 P78329 3/20 0.38
CYP4A11 Q02928 3/20 0.38
THRB P10828 1/20 0.38
HTT P42858 1/20 0.37
MMP8 P22894 1/20 0.36
TRPA1 O75762 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
PRKCA P17252 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10520670 0.80 SOAT1 (0.56) SOAT1ALDH1A1LMNAHSD17B10PKM
Hydrochloric Acid SCHEMBL27516859 0.80 SOAT1 (0.56) SOAT1ALDH1A1LMNAHSD17B10PKM
SCHEMBL126096 0.79
SCHEMBL27452723 0.79 SOAT1 (0.61) SOAT1ALDH1A1LMNAHSD17B10PKM
SCHEMBL27738039 0.79 SOAT1 (0.61) SOAT1ALDH1A1LMNAHSD17B10PKM
Diethyl Pyrocarbonate SCHEMBL15582 0.79 SOAT1 (1.00) SOAT1ALDH1A1LMNAHSD17B10PKM
Diethyl Pyrocarbonate SCHEMBL30366210 0.79 SOAT1 (1.00) SOAT1ALDH1A1LMNAHSD17B10PKM
SCHEMBL1537712 0.79 ELANE (0.37) SOAT1ALDH1A1PRKCATSHR
SCHEMBL9389500 0.77 SOAT1 (0.41) SOAT1ALDH1A1LMNAHSD17B10PKM
Hydrochloric Acid SCHEMBL29726512 0.77 CYP4F2 (0.52) SOAT1ALDH1A1LMNAHSD17B10PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114080380-B 2- (2, 4, 5-Trimethylcyclohex-2-en-1-yl) acetaldehyde and derivatives and their use as fragrance chemicals 巴斯夫欧洲公司 2024-05-28 CN disclosed
CN-114080380-A 2- (2,4, 5-trimethylcyclohex-2-en-1-yl) acetaldehyde and derivatives and their use as fragrance chemicals 巴斯夫欧洲公司 2022-02-22 CN disclosed
EP-0796243-B1 DIAMINOCYCLOBUTENE-3,4-DIONES AMERICAN HOME PROD (US) 1999-01-27 EP disclosed
EP-0796243-A1 DIAMINOCYCLOBUTENE-3,4-DIONES AMERICAN HOME PRODUCTS CORPORATION (US) 1997-09-24 EP disclosed
US-5536741-A SMOOTH MUSCLE RELAXANTS AMERICAN HOME PRODUCTS CORPORATION (US) 1996-07-16 US disclosed
US-5536731-A SMOOTH MUSCLE RELAXANTS AMERICAN HOME PRODUCTS CORPORATION (US) 1996-07-16 US disclosed
US-5530025-A SMOOTH MUSCLE RELAXANTS AMERICAN HOME PRODUCTS CORPORATION (US) 1996-06-25 US disclosed
WO-1996015103-A1 DIAMINOCYCLOBUTENE-3,4-DIONES AMERICAN HOME PRODUCTS CORPORATION (US) 1996-05-23 WO disclosed
US-5512585-A MUSCLE RELAXANT AMERICAN HOME PRODUCTS CORPORATION (US) 1996-04-30 US disclosed
US-5464867-A SMOOTH MUSCLE RELAXANTS AMERICAN HOME PRODUCTS CORPORATION (US) 1995-11-07 US disclosed