SCHEMBL8370911

SCHEMBL8370911

Cn1ncc2c1Nc1ccccc1N(C(=O)c1ccc(CNC(=O)N3CCN(Cc4cc(O)cc(O)c4)CC3)cc1F)C2

nearest known ligand 0.72

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AVPR1A P37288 20/20 0.72
OXTR P30559 4/20 0.72
AVPR2 P30518 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4699230 0.92 AVPR1A (0.72) AVPR1AOXTRAVPR2
SCHEMBL4828696 0.88 AVPR1A (0.56) AVPR1AOXTRAVPR2
SCHEMBL4695457 0.87 AVPR1A (0.86) AVPR1AOXTRAVPR2
SCHEMBL4837556 0.87 AVPR1A (0.56) AVPR1AOXTRAVPR2
SCHEMBL4697703 0.86 AVPR1A (0.85) AVPR1AOXTRAVPR2
SCHEMBL2598091 0.84 AVPR1A (1.00) AVPR1AOXTRAVPR2
SCHEMBL31737367 0.84 AVPR1A (1.00) AVPR1AOXTRAVPR2
Hydrochloric Acid SCHEMBL29580282 0.83 AVPR1A (0.99) AVPR1AOXTRAVPR2
Hydrochloric Acid SCHEMBL5428661 0.83 AVPR1A (0.99) AVPR1AOXTRAVPR2
SCHEMBL2629273 0.81 AVPR1A (0.55) AVPR1AOXTRAVPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003016316-A1 DIAZACYCLOALKANES AS OXYTOCIN AGONISTS FERRING B.V. (NL) 2003-02-27 WO disclosed