⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4863958 | 0.96 | — | — | |
| SCHEMBL5322556 | 0.70 | — | — | |
| SCHEMBL12722698 | 0.67 | — | — | |
| SCHEMBL8821761 | 0.67 | — | — | |
| Nitromethane SCHEMBL22721208 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL28071035 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL4508368 | 0.64 | — | — | |
| Methylamine SCHEMBL4610495 | 0.61 | — | — | |
| SCHEMBL9867848 | 0.61 | — | — | |
| SCHEMBL22230615 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637310-B1 | WATER-SOLUBLE RETINOIDS | CIBA GEIGY AG (CH) | 1999-01-20 | — | — | EP | claimed |
| EP-0261911-B1 | PROCESS FOR PREPARING RETINOYL CHLORIDES | McNeilab, Inc. (US) | 1991-08-21 | — | — | EP | claimed |
| EP-0711276-A1 | PROCESS FOR THE PREPARATION OF N-(4-HYDROXYPHENYL)-RETINAMIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-05-15 | — | — | EP | disclosed |
| EP-0711276-A1 | PROCESS FOR THE PREPARATION OF N-(4-HYDROXYPHENYL)-RETINAMIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995003274-A1 | PROCESS FOR THE PREPARATION OF N-(4-HYDROXYPHENYL)-RETINAMIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1995-02-02 | — | — | WO | disclosed |
| WO-1995003274-A1 | PROCESS FOR THE PREPARATION OF N-(4-HYDROXYPHENYL)-RETINAMIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1995-02-02 | — | — | WO | disclosed |