SCHEMBL8373393

SCHEMBL8373393

CCCCCCCCCCCCCCOCC(COC)OCC(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 9/20 0.51
LPAR3 Q9UBY5 9/20 0.51
USP2 O75604 1/20 0.49
LPAR2 Q9HBW0 6/20 0.48
CES2 O00748 2/20 0.47
PLA2G2C Q5R387 2/20 0.47
LPAR6 P43657 5/20 0.45
LPAR4 Q99677 5/20 0.45
LPAR5 Q9H1C0 5/20 0.45
TLR2 O60603 2/20 0.45
HTT P42858 1/20 0.44
PRKD3 O94806 1/20 0.43
PRKCG P05129 1/20 0.43
PRKCB P05771 1/20 0.43
PRKCA P17252 1/20 0.43
PRKCH P24723 1/20 0.43
PRKCI P41743 1/20 0.43
PRKCE Q02156 1/20 0.43
PRKCQ Q04759 1/20 0.43
PRKCZ Q05513 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9479138 1.00 LPAR1 (0.51) LPAR1LPAR3USP2LPAR2CES2
SCHEMBL9479107 1.00 LPAR1 (0.51) LPAR1LPAR3USP2LPAR2CES2
SCHEMBL570522 1.00 LPAR1 (0.51) LPAR1LPAR3USP2LPAR2CES2
SCHEMBL9479464 1.00 LPAR1 (0.51) LPAR1LPAR3USP2LPAR2CES2
SCHEMBL5548977 0.95 LPAR1 (0.55) LPAR1LPAR3USP2LPAR2CES2
SCHEMBL12341018 0.90 LPAR1 (0.51) LPAR1LPAR3USP2LPAR2CES2
SCHEMBL9162390 0.90 USP2 (0.53) LPAR1LPAR3USP2LPAR2CES2
SCHEMBL9479112 0.86 LPAR1 (0.38) LPAR1LPAR3USP2LPAR2PLA2G2C
SCHEMBL9479653 0.86 LPAR1 (0.54) LPAR1LPAR3USP2LPAR2PLA2G2C
SCHEMBL501728 0.86 LPAR1 (0.54) LPAR1LPAR3USP2LPAR2PLA2G2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524145-B1 Multifunctional additives for lubricants CIBA GEIGY AG (CH) 1999-01-27 EP disclosed
US-5320764-A Multifunctional lubricant additives CIBA-GEIGY CORPORATION (US) 1994-06-14 US disclosed
EP-0354871-B1 Corrosion inhibition CIBA GEIGY AG (CH) 1993-11-24 EP disclosed
EP-0524145-A1 Multifunctional additives for lubricants CIBA-GEIGY AG (CH) 1993-01-20 EP disclosed
US-5176850-A Corrosion Inhibitors CIBA-GEIGY CORPORATION (US) 1993-01-05 US disclosed
US-5013482-A Ether acids CIBA-GEIGY CORPORATION (US) 1991-05-07 US disclosed
EP-0354871-A2 Corrosion inhibition CIBA-GEIGY AG (CH) 1990-02-14 EP disclosed