SCHEMBL8375144

SCHEMBL8375144

FC(F)(F)C(F)(C(F)(F)F)C1(F)C(F)(F)C(F)(F)C(F)(Br)C(F)(F)C1(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9820526 0.97
SCHEMBL1279732 0.85
SCHEMBL1066191 0.82
SCHEMBL1279347 0.79
SCHEMBL1280072 0.77
SCHEMBL11036302 0.74
SCHEMBL11008247 0.72
SCHEMBL9862858 0.72 MEN1 (0.44)
SCHEMBL8073310 0.72
SCHEMBL9820427 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2849471-B2 1999-01-20 JP claimed
EP-0478686-B1 FLUORINE AND PHOSPHOROUS-CONTAINING AMPHIPHILIC MOLECULES WITH SURFACTANT PROPERTIES APPLICATIONS ET TRANSFERTS DE TECHNOLOGIES AVANCEES ATTA (FR) 1993-08-11 EP claimed
EP-0255443-B1 NEW POLYHYDROXYLATED AND HIGHLY FLUORINATED COMPOUNDS, THEIR PREPARATION AND THEIR USE AS SURFACTANTS ATTA (FR) 1992-10-14 EP claimed
EP-0478686-A1 FLUORINE AND PHOSPHOROUS-CONTAINING AMPHIPHILIC MOLECULES WITH SURFACTANT PROPERTIES. ATTA (FR) 1992-04-08 EP claimed
US-4985550-A Sugar derivatives, oxygen carriers, artificial blood ALLIANCE PHARMACEUTICAL CORP. (US) 1991-01-15 US claimed
WO-1990015807-A1 FLUORINE AND PHOSPHOROUS-CONTAINING AMPHIPHILIC MOLECULES WITH SURFACTANT PROPERTIES APPLICATIONS ET TRANSFERTS DE TECHNOLOGIES AVANCÉES (FR) 1990-12-27 WO claimed
EP-0255443-A1 New polyhydroxylated and highly fluorinated compounds, their preparation and their use as surfactants ATTA (FR) 1988-02-03 EP claimed
US-5344930-A Blood substitutes to carry oxygen ALLIANCE PHARMACEUTICAL CORP. (US) 1994-09-06 US disclosed
EP-0478686-B1 FLUORINE AND PHOSPHOROUS-CONTAINING AMPHIPHILIC MOLECULES WITH SURFACTANT PROPERTIES APPLICATIONS ET TRANSFERTS DE TECHNOLOGIES AVANCEES ATTA (FR) 1993-08-11 EP disclosed
EP-0255443-B1 NEW POLYHYDROXYLATED AND HIGHLY FLUORINATED COMPOUNDS, THEIR PREPARATION AND THEIR USE AS SURFACTANTS ATTA (FR) 1992-10-14 EP disclosed
EP-0478686-A1 FLUORINE AND PHOSPHOROUS-CONTAINING AMPHIPHILIC MOLECULES WITH SURFACTANT PROPERTIES. ATTA (FR) 1992-04-08 EP disclosed
US-4985550-A Sugar derivatives, oxygen carriers, artificial blood ALLIANCE PHARMACEUTICAL CORP. (US) 1991-01-15 US disclosed
WO-1990015807-A1 FLUORINE AND PHOSPHOROUS-CONTAINING AMPHIPHILIC MOLECULES WITH SURFACTANT PROPERTIES APPLICATIONS ET TRANSFERTS DE TECHNOLOGIES AVANCÉES (FR) 1990-12-27 WO disclosed
EP-0255443-A1 New polyhydroxylated and highly fluorinated compounds, their preparation and their use as surfactants ATTA (FR) 1988-02-03 EP disclosed