SCHEMBL8375465

SCHEMBL8375465

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nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA4 P43681 1/20 0.31
BCL2A1 Q16548 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20656796 0.78 MEN1 (0.37) TSHRBCL2A1
SCHEMBL20126000 0.78 MEN1 (0.37) TSHRBCL2A1
SCHEMBL13563793 0.77 TSHR (0.32) TSHR
SCHEMBL17665961 0.77 TSHR (0.33) TSHRBCL2A1
SCHEMBL541432 0.77 TSHR (0.33) TSHRBCL2A1
SCHEMBL27695608 0.77 TSHR (0.33) TSHRBCL2A1
SCHEMBL22917645 0.75 TSHR (0.36) TSHRBCL2A1
SCHEMBL7051345 0.75 TSHR (0.37) TSHRBCL2A1
SCHEMBL29539704 0.75 TSHR (0.36) TSHRBCL2A1
SCHEMBL10626427 0.74 TSHR (0.42) TSHRCHRNB2CHRNB4CHRNA3CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5883211-A Thermoreversible hydrogels comprising linear copolymers and their use in electrophoresis ACLARA BIOSCIENCES, INC. (US) 1999-03-16 US disclosed