Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL722023 | 1.00 | TSHR (0.68) | TSHRALDH1A1FAAHTRPV1F7 | |
| SCHEMBL722024 | 1.00 | TSHR (0.68) | TSHRALDH1A1FAAHTRPV1F7 | |
| SCHEMBL1030027 | 1.00 | TSHR (0.68) | TSHRALDH1A1FAAHTRPV1F7 | |
| SCHEMBL1032204 | 1.00 | TSHR (0.68) | TSHRALDH1A1FAAHTRPV1F7 | |
| SCHEMBL25185230 | 0.97 | TSHR (0.65) | TSHRALDH1A1FAAHTRPV1F7 | |
| SCHEMBL25178888 | 0.97 | TSHR (0.65) | TSHRALDH1A1FAAHTRPV1F7 | |
| SCHEMBL15466950 | 0.95 | TSHR (0.64) | TSHRALDH1A1FAAHTRPV1F7 | |
| SCHEMBL19895403 | 0.93 | TSHR (0.59) | TSHRALDH1A1TRPV1F7F3 | |
| SCHEMBL25182434 | 0.92 | TSHR (0.74) | TSHRALDH1A1FAAHTRPV1F7 | |
| SCHEMBL25178068 | 0.92 | TSHR (0.74) | TSHRALDH1A1FAAHTRPV1F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916983-A | Biologically active compounds by catalytic olefin metathesis | BEND RESEARCH, INC. (US) | 1999-06-29 | — | — | US | disclosed |