Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375649 | 1.00 | CYP2C9 (0.45) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL8375645 | 1.00 | CYP2C9 (0.45) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL8375641 | 1.00 | CYP2C9 (0.45) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL3273315 | 0.98 | CYP2C9 (0.49) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL10910260 | 0.98 | CYP2C9 (0.49) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL7900636 | 0.98 | CYP2C9 (0.49) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL7900638 | 0.98 | CYP2C9 (0.49) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL8379717 | 0.98 | CYP2C9 (0.49) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL8211345 | 0.98 | CYP2C9 (0.49) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL7900631 | 0.98 | CYP2C9 (0.49) | CYP2C9MAPTALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958290-A | ELECTROOPTICAL APPARATUS WITH DIELECTRIC LIQUID CRYSTALS FOR RADIATION TRANSPARENT MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-09-28 | — | — | US | disclosed |
| US-5344587-A | Nitriles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-09-06 | — | — | US | disclosed |