SCHEMBL8375812

SCHEMBL8375812

CCCCCCCCCCOC(=O)c1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.79
TSHR P16473 3/20 0.79
LMNA P02545 2/20 0.79
CYP1A2 P05177 2/20 0.79
CYP2C19 P33261 2/20 0.79
CYP2D6 P10635 1/20 0.79
MAPK1 P28482 1/20 0.79
NR1H2 P55055 1/20 0.79
RNASEL Q05823 1/20 0.79
SMN1; SMN2 Q16637 1/20 0.79
ALDH1A1 P00352 2/20 0.68
CHRM1 P11229 1/20 0.68
SLC6A2 P23975 1/20 0.68
KDR P35968 1/20 0.68
TDP1 Q9NUW8 1/20 0.68
NPC1 O15118 1/20 0.68
MAPT P10636 1/20 0.68
RAB9A P51151 1/20 0.68
AKR1C4 P17516 1/20 0.59
AKR1C3 P42330 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9300662 1.00 ESR1 (0.79) ESR1TSHRLMNACYP1A2CYP2C19
SCHEMBL9639785 1.00 ESR1 (0.79) ESR1TSHRLMNACYP1A2CYP2C19
SCHEMBL7697420 1.00 ESR1 (0.79) ESR1TSHRLMNACYP1A2CYP2C19
SCHEMBL9300044 0.98 ESR1 (0.81) ESR1TSHRLMNACYP1A2CYP2C19
SCHEMBL1263037 0.95 ESR1 (0.87) ESR1TSHRLMNACYP1A2CYP2C19
SCHEMBL1042112 0.95 ESR1 (0.87) ESR1TSHRLMNACYP1A2CYP2C19
SCHEMBL19834333 0.95 ESR1 (0.87) ESR1TSHRLMNACYP1A2CYP2C19
Nonyl 4-Hydroxybenzoate SCHEMBL187991 0.95 ESR1 (0.87) ESR1TSHRLMNACYP1A2CYP2C19
SCHEMBL66483 0.95 ESR1 (0.87) ESR1TSHRLMNACYP1A2CYP2C19
SCHEMBL1041302 0.95 ESR1 (0.87) ESR1TSHRLMNACYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5891359-A FLUOROTRIESTERAROMATIC COMPOUND FOR LIQUID CRYSTALS SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1999-04-06 US disclosed
US-5482652-A CYCLOHEXANECARBOXYLIC ESTERS WITH PYRIMIDINE COMPOUNDS CANON KABUSHIKI KAISHA (JP) 1996-01-09 US disclosed
EP-0422996-B1 Liquid crystal compound SHOWA SHELL SEKIYU (JP) 1995-04-12 EP disclosed
US-5389296-A High speed responsiveness to an electric field and less temperature dependancy; ferroelectric chiral sematic; contains a mesomorphic compound CANON KABUSHIKI KAISHA (JP) 1995-02-14 US disclosed
US-5328641-A Naphthalene ester derivatives with trifluoromethyl groups SHOWA SHELL SEKIYU KABUSHIKI KAISHA 1994-07-12 US disclosed
EP-0293910-B1 Liquid crystal composition and liquid crystal device containing same CANON KK (JP) 1994-02-02 EP disclosed
EP-0541509-A2 Liquid crystal composition and liquid crystal device containing same CANON KABUSHIKI KAISHA (JP) 1993-05-12 EP disclosed
US-5207947-A Trifluoroalkyl diaryl triesters; antiferroelectricity; electrooptics SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1993-05-04 US disclosed
US-5139697-A Smaller temperature dependence of response speed CANON KABUSHIKI KAISHA (JP) 1992-08-18 US disclosed
EP-0326086-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 1992-07-08 EP disclosed
EP-0469975-A1 Liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1992-02-05 EP disclosed
EP-0326086-A2 Liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1989-08-02 EP disclosed
EP-0293910-A2 Liquid crystal composition and liquid crystal device containing same CANON KABUSHIKI KAISHA (JP) 1988-12-07 EP disclosed