Bicarbonate

Bicarbonate

SCHEMBL8376231

O.O=C(O)O.[AlH3].[Ni]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL5613815 0.94 CA1 (0.71)
Bicarbonate SCHEMBL9950133 0.94
Bicarbonate SCHEMBL904704 0.94
Bicarbonate SCHEMBL1315914 0.94
Bicarbonate SCHEMBL904554 0.94
Bicarbonate SCHEMBL8105626 0.94
Bicarbonate SCHEMBL5553271 0.94 CA1 (0.71)
Bicarbonate SCHEMBL3787736 0.94
Bicarbonate SCHEMBL14562563 0.94 CA1 (0.71)
Bicarbonate SCHEMBL5074467 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0737669-B1 Reductive amination processes for the selective production of aminoethylethanolamine UNION CARBIDE CHEM PLASTIC (US) 1999-09-22 EP disclosed
US-5891820-A REDUCTIVE AMINATION CATALYST COMPRISING BASIC NICKEL ALUMINUM CARBONATE IMPREGNATED WITH RHENIUM PROMOTER UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-04-06 US disclosed
EP-0478075-B1 Decarboxylation processes UNION CARBIDE CHEM PLASTIC (US) 1998-11-11 EP disclosed
EP-0476780-B1 Catalytic processes for the preparation of bridged nitrogen-containing compounds UNION CARBIDE CHEM PLASTIC (US) 1998-05-06 EP disclosed
US-5600000-A USING METAL CATALYST ON TRANSITIONAL ALUMINA CARRIER UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1997-02-04 US disclosed
EP-0737669-A1 Reductive amination processes for the selective production of aminoethylethanolamine UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1996-10-16 EP disclosed
EP-0476785-B1 Processes for the preparation of aminoethers OSI SPECIALTIES INC (US) 1995-12-06 EP disclosed
US-5280120-A Di(methyl or phenyl) carbonate UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-01-18 US disclosed
US-5247103-A Decarboxylation catalysts UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-09-21 US disclosed
US-5245032-A CATALYTIC PROCESSES FOR THE PREPARATION OF N,N,N-TRISUBSTITUTED NITROGEN-CONTAINING COMPOUNDS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-09-14 US disclosed
EP-0476784-A1 Processes for the preparation of ethers UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1992-03-25 EP disclosed
EP-0476780-A2 Catalytic processes for the preparation of bridged nitrogen-containing compounds UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1992-03-25 EP disclosed
EP-0476781-A2 Catalytic process for the preparation of bridged nitrogen-containing compounds UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1992-03-25 EP disclosed
EP-0476785-A1 Processes for the preparation of aminoethers OSi Specialties, Inc. (US) 1992-03-25 EP disclosed
EP-0476782-A1 Catalytic processes for the preparation of N,N,N-trisubstituted nitrogen-containing compounds UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1992-03-25 EP disclosed
EP-0476786-A2 Processes for the preparation of cyclic ethers UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1992-03-25 EP disclosed
US-5064804-A Metal vanadates, molybdates, or tungsttes for hydrolysis UNION CARBIDE CHEMICALS AND PLASTICS TECHNOLOGY CORPORATION (US) 1991-11-12 US disclosed
US-4967018-A HYDROLYSIS OF ALKYLENE OXIDE UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1990-10-30 US disclosed
EP-0318099-A2 Monoalkylene glycol production using mixed metal framework compositions UNION CARBIDE CORPORATION (US) 1989-05-31 EP disclosed
US-4623533-A CATALYTIC OXIDATION OF HYDROGEN SULFIDE BASF AKTIENGESELLSCHAFT (DE) 1986-11-18 US disclosed